Analysis of Factors Affecting the Occurrence of Ectopic Pregnancy: Risk Factors, Early Detection, and Preventive Strategies
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Abstract
Ectopic pregnancy is a leading cause of maternal morbidity and mortality, with several factors contributing to its occurrence. This research aims to analyze the causes and risk factors associated with ectopic pregnancy, focusing on tubal factors, hormonal imbalances, infections, previous surgeries, age, smoking, contraceptive use, and obesity. A comprehensive review of existing literature was conducted, and primary data was collected through surveys and medical records analysis. The study found that tubal factors, pelvic inflammatory disease, and previous surgeries were the most significant risk factors. Additionally, obesity, smoking, advanced maternal age, and contraceptive use, especially IUDs, were identified as contributing factors. Unexpectedly, emotional stress was found to have a notable association with ectopic pregnancy. The findings suggest the need for public health interventions focusing on lifestyle changes, mental health support, and patient education about contraceptive risks. Preventive strategies such as early screening for high-risk individuals, stress management, and enhanced contraceptive counseling are recommended. Future research should explore the psychological aspects of ectopic pregnancy, the impact of obesity on reproductive health, and the development of improved detection methods and guidelines for contraceptive use.
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Assiri, A., Al-Tawfiq, J. A., Al-Rabeeah, A. A., Al-Rabiah, F. A., Al-Hajjar, S., Al-Barrak, A., Flemban, H., Al-Nassir, W. N., Balkhy, H. H., & Al-Hakeem, R. F. (2013). Epidemiological, demographic, and clinical characteristics of 47 cases of Middle East respiratory syndrome coronavirus disease from Saudi Arabia: a descriptive study. The Lancet Infectious Diseases, 13(9), 752–761.
Bouyer, J., Coste, J., Shojaei, T., Pouly, J.-L., Fernandez, H., Gerbaud, L., & Job-Spira, N. (2003). Risk factors for ectopic pregnancy: a comprehensive analysis based on a large case-control, population-based study in France. American Journal of Epidemiology, 157(3), 185–194.
Chen, H., Guo, J., Wang, C., Luo, F., Yu, X., Zhang, W., Li, J., Zhao, D., Xu, D., & Gong, Q. (2020). Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records. The Lancet, 395(10226), 809–815.
Crochet, J. R., Bastian, L. A., & Chireau, M. V. (2013). Does this woman have an ectopic pregnancy?: the rational clinical examination systematic review. Jama, 309(16), 1722–1729.
Dialani, V., & Levine, D. (2004). Ectopic pregnancy: a review. Ultrasound Quarterly, 20(3), 105–117.
Gracia, C. R., & Barnhart, K. T. (2001). Diagnosing ectopic pregnancy: decision analysis comparing six strategies. Obstetrics & Gynecology, 97(3), 464–470.
Häyrinen, K., Saranto, K., & Nykänen, P. (2008). Definition, structure, content, use and impacts of electronic health records: a review of the research literature. International Journal of Medical Informatics, 77(5), 291–304.
Karaer, A., Avsar, F. A., & Batioglu, S. (2006). Risk factors for ectopic pregnancy: A case‐control study. Australian and New Zealand Journal of Obstetrics and Gynaecology, 46(6), 521–527.
Katz, M. H. (2003). Multivariable analysis: a primer for readers of medical research. Annals of Internal Medicine, 138(8), 644–650.
Kim, W. O. (2012). Institutional review board (IRB) and ethical issues in clinical research. Korean Journal of Anesthesiology, 62(1), 3.
Kraemer, H. C., & Blasey, C. (2015). How many subjects?: Statistical power analysis in research. Sage publications.
Leke, R. J., Goyaux, N., Matsuda, T., & Thonneau, P. F. (2004). Ectopic pregnancy in Africa: a population-based study. Obstetrics & Gynecology, 103(4), 692–697.
Li, C., Zhao, W.-H., Meng, C.-X., Ping, H., Qin, G.-J., Cao, S.-J., Xi, X., Zhu, Q., Li, X.-C., & Zhang, J. (2014). Contraceptive use and the risk of ectopic pregnancy: a multi-center case-control study. Plos One, 9(12), e115031.
Liu, J. Z., Erlich, Y., & Pickrell, J. K. (2017). Case–control association mapping by proxy using family history of disease. Nature Genetics, 49(3), 325–331.
Marion, L. L., & Meeks, G. R. (2012). Ectopic pregnancy: history, incidence, epidemiology, and risk factors. Clinical Obstetrics and Gynecology, 55(2), 376–386.
Moini, A., Hosseini, R., Jahangiri, N., Shiva, M., & Akhoond, M. R. (2014). Risk factors for ectopic pregnancy: A case–control study. Journal of Research in Medical Sciences: The Official Journal of Isfahan University of Medical Sciences, 19(9), 844.
Orazulike, N. C., & Konje, J. C. (2013). Diagnosis and management of ectopic pregnancy. Women’s Health, 9(4), 373–385.
Reekie, J., Donovan, B., Guy, R., Hocking, J. S., Kaldor, J. M., Mak, D. B., Pearson, S., Preen, D., Stewart, L., & Ward, J. (2018). Risk of pelvic inflammatory disease in relation to chlamydia and gonorrhea testing, repeat testing, and positivity: a population-based cohort study. Clinical Infectious Diseases, 66(3), 437–443.
Refaat, B., Dalton, E., & Ledger, W. L. (2015). Ectopic pregnancy secondary to in vitro fertilisation-embryo transfer: pathogenic mechanisms and management strategies. Reproductive Biology and Endocrinology, 13, 1–18.
Sedgwick, P. (2013). Convenience sampling. Bmj, 347.
Shao, R., Feng, Y., Zou, S., Weijdegård, B., Wu, G., Brännström, M., & Billig, H. (2012). The role of estrogen in the pathophysiology of tubal ectopic pregnancy. American Journal of Translational Research, 4(3), 269.
Shaw, J. L. V, Dey, S. K., Critchley, H. O. D., & Horne, A. W. (2010). Current knowledge of the aetiology of human tubal ectopic pregnancy. Human Reproduction Update, 16(4), 432–444.
Simms, I., Stephenson, J. M., Mallinson, H., Peeling, R. W., Thomas, K., Gokhale, R., Rogers, P. A., Hay, P., Oakeshott, P., & Hopwood, J. (2006). Risk factors associated with pelvic inflammatory disease. Sexually Transmitted Infections, 82(6), 452–457.
Sivalingam, V. N., Duncan, W. C., Kirk, E., Shephard, L. A., & Horne, A. W. (2011). Diagnosis and management of ectopic pregnancy. Journal of Family Planning and Reproductive Health Care, 37(4), 231–240.
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